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    louse

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    louse
    I
    louse1 /laʊs/ noun [countable]
     Language: Old English
     Origin: lus
    1. (plural lice /laɪs/) a small insect that lives on the hair or skin of people or animals
    2. (plural louses) informal someone who is nasty and unpleasant

    II
    louse2 verb
         
    louse something ↔ up phrasal verb informal
      to make something worse rather than better, or to spoil something
       SYN  mess up:
        That idiot loused up my chance of promotion.